Investigate multi-scale mechanical stimulation

NanoSurface nanopatterned culture surfaces provide a cellular microenvironment that mimics the aligned architecture of the native extracellular matrix, promoting cellular structural and functional development. The NanoSurface Cytostretcher integrates flexible NanoSurface culture chambers with the ability to stimulate your cultures with cyclic mechanical stretch. Versatile software enables programming of a wide array of stretch protocols for tremendous investigative flexibility.

System specifications:

  • Instrument footprint: 300 x 100 x 60 mm

  • Instrument mass: 2 kg

  • Nanopatterned flexible cell culture chamber surface topography dimensions: 800-800-600 nm (ridge-groove-depth)

  • Culture area: 144 mm2 or 25 mm2

  • Throughput: up to 6 parallel chambers per instrument

  • Connectivity: USB & onboard memory for stored protocols

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Atomic Force Microscopy imaging of NanoSurface culture area with 800-800-600 nm (ridge-groove-depth) dimensions.

Atomic Force Microscopy imaging of NanoSurface culture area with 800-800-600 nm (ridge-groove-depth) dimensions.

Elastomeric culture chamber with 5 mm x 5 mm culture area. Use up to 6 chambers in parallel in a single Cytostretcher instrument.

Elastomeric culture chamber with 5 mm x 5 mm culture area. Use up to 6 chambers in parallel in a single Cytostretcher instrument.

Elastomeric culture chamber with 12 mm x 12 mm culture area. Use up to 3 chambers in parallel in a single Cytostretcher instrument.

Elastomeric culture chamber with 12 mm x 12 mm culture area. Use up to 3 chambers in parallel in a single Cytostretcher instrument.

All-in-one stretching system

  • The NanoSurface Cytostretcher elongates flexible culture chambers to provide cyclic mechanical strain to cultured cells. With a small footprint and self-cobntained design, the NanoSurface Cytostretcher eliminates bulky external controllers.

  • A transparent viewing window prevents contamination while monitoring cultured cells, or while transporting the device between a culture hood and an incubator.

  • Elastomeric cell culture chambers are available in two sizes, and can be ordered with biomimetic nanoscale surface topography either in parallel or perpendicular to the direction of applied stretch, or with unpatterned "flat" surface topography.

  • The NanoSurface Cytostretcher is programmable using a versatile and intuitive NaOMI software.

Cytomechanics, unlocked

  • The NanoSurface Operational Mechanics Interface - NaOMI - enables complete control of stretching parameters and cyclic strain protocols for maximum investigative flexibility. Compatible with both Windows and Mac OS, NaOMI software provides a straighforward and powerful user interface for automated operation of the NanoSurface Cytostretcher.

  • USB connectivity allows for easy operation. Software logging automatically records experimental details. Users can program elongation length, holding time, and stretching speed independently for each stretch cycle.