NanoSurface Cultureware Products


More Mature Cell and Tissue Cultures, Faster

NanoSurface Cultureware provides your cells and tissues a biomimetic surface to improve the physiological relevance of your experiments. Shortly after plating, cells cultured on NanoSurface Cultureware exhibit enhanced structural and phenotypic development when compared to cells grown on conventional dishes. NanoSurface topography promotes cytoskeletal reorganization, cellular alignment, and functional development. NanoSurface Cultureware is available in familiar standard formats, featuring No. 1.5 glass-bottom wells for high-quality imaging. 

Benefits of NanoSurface Cultureware

High-quality Imaging

Compatible with high-magnification, high-NA transmitted light and fluorescence microscopy techniques. No spectral loss across commonly used fluorophores.

Reproducibly Structured Cell Cultures

Highly uniform, precise, and accurate nanopatterns ensure that your results are consistent from plate to plate.

Industry Standard Culture Formats

Cultureware comes in a variety of ANSI/SLAS compliant form factors to guarantee compatibility with existing instrumentation and hardware. 

Biomimetic Technology

Nanoscale topography mimics the aligned architecture of the extracellular matrix. 


NanoSurface Dishes Promote the Structural and Phenotypic Development of Many Cell Types

  hiPSC-CM / Conventional Dish

hiPSC-CM / Conventional Dish

  EA.hy926 Human Endothelial Cells / Conventional

EA.hy926 Human Endothelial Cells / Conventional

  hiPSC-CM / NanoSurface Cultureware

hiPSC-CM / NanoSurface Cultureware

  EA.hy926 Human Endothelial Cells / NanoSurface

EA.hy926 Human Endothelial Cells / NanoSurface

Examples of cells cultures that would benefit with the use of NanoSurface Cultureware:

  • Fibroblasts

  • Cancer cells

  • Induced pluripotent stem cells

  • Mesenchymal stem cells

  • Human embryonic stem cells

  • Skeletal muscle cells

  • Smooth muscle cells

  • Neuronal cells

  • Cardiomyocytes

  • Endothelial cells

  • Epithelial cells

  • And many more


Conventional Orientation HEAT Map CM
NanoSurface Cultureware Orientation HEAT Map CM

NanoSurface Cultureware

NanoSurface Cultureware features a nanopatterned culture surface which provides a cellular microenvironment that mimics the aligned architecture of the native extracellular matrix – improving physiological relevance by promoting development. Cells can align, elongate, grow, and even migrate along the pattern while exhibiting more physiologically representative structural and functional phenotypes. 

Conventional Dish

Conventional cultureware does not utilize biomimetic surface topography, which results in random structural orientation. The disorganized isotropic cell and tissue architectures result in immature functional phenotypes that do not reproduce in vivo function. These inaccuracies lead to imprecise, hard-to-reproduce results and wasted time and effort.


Biomimetic Nanoscale Surface Topography Imitates the Aligned Structure of the Native ECM

AFM Image of NanoSurface Culture Surface

Nanopatterned culture surfaces allow cells to align, elongate, grow, and even migrate along the nanopattern while exhibiting more physiologically representative structural and functional phenotypes.

  The underlying matrix of the native myocardium has an aligned architecture (scale bar 10 µm).

The underlying matrix of the native myocardium has an aligned architecture (scale bar 10 µm).