More mature cell and tissue cultures, faster

NanoSurface Cultureware structures cultured cells and tissues to improve physiological relevance. Shortly after plating, cells cultured in NanoSurface Cultureware exhibit enhanced structural and phenotypic development as compared to cells cultured in conventional culture dishes. NanoSurface topography induces cytoskeletal reorganization and cellular alignment. NanoSurface Cultureware is available in familiar standard formats, featuring No. 1.5 glass-bottom wells for high quality imaging.

  • Single-well 35mm Ø dish (20mm Ø pattern area)

  • 6-well plate with 35mm Ø wells  (20mm Ø pattern area)

  • 24-well plate with 20mm Ø wells (full well area patterned)

  • 96-well plate with 5mm Ø wells (full well area patterned)

  • No. 1.5 glass coverslips


NanoSurface plates rapidly structure and mature many cell types.

  hiPSC-CM / Conventional

hiPSC-CM / Conventional

  EA.hy926 Human Endothelial Cells / Conventional

EA.hy926 Human Endothelial Cells / Conventional

  hiPSC-CM / NanoSurface

hiPSC-CM / NanoSurface

  EA.hy926 Human Endothelial Cells / NanoSurface

EA.hy926 Human Endothelial Cells / NanoSurface

  • Cardiomyocytes

  • Skeletal muscle cells

  • Smooth muscle cells

  • Endothelial cells

  • Human embryonic stem cells

  • Induced pluripotent stem cells

  • Mesenchymal stem cells

  • Fibroblasts

  • Epithelial cells

  • Cancer cells


Conventional Orientation Map CM
NanoSurface Orientation Map CM

NanoSurface Dish

  • On NanoSurface dishes, cardiomyocytes align to the surface topography, elongate in the direction of the nanopattern, and exhibit uniform anisotropic contraction patterns, with enhanced contractile force and conduction velocity.

Conventional Dish

  • Without biomimetic surface topography, cardiomyocytes exhibit random orientation, disorganized contraction patterns, and immature functional phenotypes on conventional culture surface.


Biomimetic nanoscale surface topography imitates the aligned structure of the native extracellular matrix.

AFM Image of NanoSurface Culture Surface

NanoSurface nanopatterned culture surfaces provide a cellular microenvironment that mimics the aligned architecture of the native extracellular matrix, promoting cellular structural and functional development.

  The underlying matrix of the native myocardium has an aligned architecture (scale bar 10 µm).

The underlying matrix of the native myocardium has an aligned architecture (scale bar 10 µm).