Mantarray™ App Notes
A Scalable Functional Model of 3D Human Neuromuscular Junctions Using the Mantarray Platform
Featuring: Mantarray Platform (Released February 2024)
This Application Note Covers:
Facile co-culture of iPSC-derived neurons & skeletal muscle into a 3D NMJ model.
Scalable, reproducible & reliable formation of 3D human NMJs with long in vitro lifetimes.
Turnkey, longitudinal collection of NMJ functional data, backed by histological evidence.
Pre-clinical Identification of Dose-dependent Cardiac Toxicity
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Featuring: Mantarray Platform (Released January 2024)
This Application Note Covers:
Turnkey scalable production of human 3D engineered heart tissues.
Label-free automated capture and analysis of functional data across 24 tissues in parallel.
In vitro validation of clinical drug toxicity and efficacy using human cell models.
Identification of optimal dosing regimens to minimize functional side-effects.
Cytostretcher™ App Notes
Application of Cyclic Uniaxial Stretch: New Tools for Understanding the Role of the Extracellular Matrix in Cell Biology
Featuring: Cytostretcher Platform (Released December 2018)
In this application note, the role and importance of the structural and mechanical components of Extracellular Matrix (ECM) are investigated and compared for C2C12 and U2OS cells.
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NanoSurface™ Plates App Notes
New Tools for Understanding the Role of the Extracellular Matrix in Cell Morphology: A Combined Photopatterning in Nanotopography Study
Featuring: NanoSurface Plates (Released December 2018)
In this application note, the differential impact of the chemical and structural components of the Extracellular Matrix (ECM) was investigated and compared to the structure and organization of HeLa cells.
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Enhancing the Development of hPSC-neurons by Engineering the Extracellular Matrix: an MEA and Microscopy Study
Featuring: NanoSurface Plates (Released November 2018)
Nanotopographically patterned transparent multiwell microelectrode arrays (MEAs) were used to study neuronal structure, network connectivity, and sensitivity to synaptic blockers in cultured hPSCneuron monolayers.
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