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Cytostretcher

Cell Stretching Instruments for Biomimetic Experiments

 
 
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Mechanically Condition Cells and Tissues

The Cytostretcher is an integrated platform for creating mechanically conditioned cell and tissue models.

The Cytostretcher family of cell stretching systems enables scientists to apply biomimetic mechanical strain to cells and tissues with ease and precision.

 
 

Cytostretcher

The Cytostretcher can be used to stretch cells on the bench-top or in a cell culture incubator.

Cytostretcher-LV

The Cytostretcher-LV can be used to perform stretching experiments on an optical microscope.

 
 

Cytostretcher Key Features

 
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Software with Unprecedented Experimental Control 

The NaOMI software allows for intuitive control of stretching protocols for Cytostretcher instruments.

Compact Design 

The Cytostretcher is extremely compact, easily integrating into your existing cell culture workflow. It can be operated on the bench-top or alongside other cultures inside a standard cell culture incubator – saving valuable space. 

  • Instrument footprint:
    280 x 102 x 65 mm

  • Control Unit footprint:
    110 x 64 x 60 mm

Convenient External Controller

The Cytostretcher External Controller is a small, lightweight module that can be magnetically attached to the exterior of a cell culture incubator to save space while being accessible. 

Run Multiple Experiments in Parallel 

Flexible Cytostretcher Chambers are available in a variety of formats, so you can mechanically condition many cultures in parallel.


Cytostretcher-LV Key Features

 
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Live View: Observe Cells While Stretching 

Image live cells during your stretch routines. The Cytostretcher-LV and Cytostretcher Chambers are compatible with transmitted light and high-NA fluorescence microscopy, including immersion objectives. 

Maintain Focus While Stretching 

The Cytostretcher-LV is the only cell mechanical stimulation system that enables consistent sample focus during stretch. 

Universal Mounting Frame K 

Allows for broad compatibility with many industry standard microscopes and stages. Other mount options are available upon request. 

Up to Six Parallel Experiments

Configure up to six 5 mm x 5mm wells or one 12mm x 12mm well:

Environmental Control Unit (ECU) for Stage-Top Incubation

The Cytostretcher-LV is compatible with an optional Environmental Control Unit (ECU) for microscope stage-top incubation. The ECU provides complete control of biological culture conditions, including temperature, humidity, and CO2 concentration. 

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NaOMI: Cell Mechanics, Unlocked

NaOMI software allows for intuitive control of stretching parameters and protocols for Cytostretcher instruments. 

  • Build simple stretch protocols, or complex multi-step stretch routines

  • Save protocols for repeated use or later modification 

  • Control stretch velocity, duration, frequency, magnitude, delay times before and after stretch, and the type of waveform used to drive the stretch protocol 

  • Computer-free operation after protocol setup 

  • Protocol graph for easy visualization 

  • Standard USB connectivity, compatible with Windows 10  

  • Intuitive user interface with powerful editing tools 

 
 
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Cytostretcher Brochure

Download the Cytostretcher product brochure for general information about Cytostretcher and Cytostretcher-LV products in a convenient PDF format. For additional information, please contact support@curibio.com.

 
 

Read the Application Notes

Application of Cyclic Uniaxial Stretch: New Tools for Understanding the Role of the Extracellular Matrix in Cell Biology

 
 

Cytostretcher Chambers

Cytostretcher Chambers are available with and without NanoSurface™ Topography

Cytostretcher Chambers are available with NanoSurface topography that mimics the aligned architecture of the native extracellular matrix, or with unpatterned “flat” surfaces. Patterned chambers are available with topographic cues either aligned in parallel or perpendicular to the direction of applied stretch.

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